Ehholo lesayensi yokuphila, i-Coenzyme Q10 ifana neparele elikhanyayo, elikhanyisa indlela yocwaningo lokulwa nokuguga. Le nto ekhona kuwo wonke amangqamuzana ayiyona nje into eyinhloko ekusetshenzisweni kwamandla, kodwa futhi iyisivikelo esibalulekile ekugugeni. Le ndatshana izocubungula izimfihlakalo zesayensi, inani lesicelo, namathemba esikhathi esizayo we-coenzyme Q10.
1. Ukuqoshwa kwesayensi kwe-coenzyme Q10
I-Coenzyme Q10 iyinhlanganisela ye-lipid encibilikayo yequinone enegama lekhemikhali elithi 2,3-dimethoxy-5-methyl-6-decisoprenyl 1,4-benzoquinone. Isakhiwo sayo samangqamuzana sakhiwe ngendandatho ye-quinone namaketanga aseceleni e-isopentenyl, okuyinikeza imisebenzi emibili yokudlulisa ama-electron kanye ne-antioxidant.
Kumetabolism yomuntu, i-coenzyme Q10 itholakala ikakhulukazi kulwelwesi lwangaphakathi lwe-mitochondria, ibamba iqhaza ochungechungeni lokudlulisa ama-electron, futhi iyisici esibalulekile ekuhlanganiseni kwe-ATP. Ngaleso sikhathi, futhi iyi-antioxidant enamandla engaqeda ama-radicals mahhala futhi ivikele ulwelwesi lwamaseli kanye ne-DNA emonakalweni we-oxidative.
Njengoba abantu bekhula, ikhono labo lokuhlanganisa i-coenzyme Q10 liyehla kancane kancane. Ucwaningo luye lwabonisa ukuthi ngemva kweminyaka engama-40, izinga le-coenzyme Q10 emzimbeni womuntu lehla cishe ngo-30% uma liqhathaniswa neminyaka engama-20, okuholela ngokuqondile ekwehleni kokusebenza kahle kwe-metabolism yamandla futhi kusheshise inqubo yokuguga.
2, Izicelo Ezinezinhlangothi Eziningi zeI-Coenzyme Q10
Emkhakheni wokulwa nokuguga, i-coenzyme Q10 ibambezela inqubo yokuguga ngokuthuthukisa ukusebenza kahle kwe-metabolism yamandla eselula kanye nomthamo we-antioxidant. Izivivinyo zemitholampilo zibonise ukuthi ngemva kokuthatha i-coenzyme Q12 ngomlomo amasonto angu-2, ukunwebeka kwesikhumba kukhuphuka ngo-25% futhi ukujula kwemibimbi kwehla ngo-15%.
Ngokuphathelene nempilo yenhliziyo nemithambo yegazi, i-coenzyme Q10 ingathuthukisa amandla e-myocardial metabolism futhi ithuthukise ukusebenza kwenhliziyo. Ucwaningo luye lwabonisa ukuthi ukufaka i-coenzyme Q10 ezigulini ezihluleka inhliziyo kunganciphisa ukufa ngo-43% kanye nengozi yokulaliswa esibhedlela ngama-31%.
Ekunakekelweni kwesikhumba, ukusetshenziswa kwezihloko zei-coenzyme Q10ingangena ijule ku-epidermis, inciphise ama-radicals mahhala, futhi inciphise umonakalo wokuthwebula izithombe. Idatha yokuhlola ibonisa ukuthi ngemva kokusebenzisa imikhiqizo ye-skincare equkethe i-coenzyme Q10 amasonto angu-8, umswakama wesikhumba ukhuphuke ngo-30% futhi imigqa emihle yehla ngo-20%.
Emkhakheni wokudla okunempilo kwezemidlalo, i-coenzyme Q10 ithuthukisa ukukhuthazela kokuzivocavoca ngokuthuthukisa ukusebenza kahle kwe-metabolism yamandla. Ucwaningo luye lwabonisa ukuthi ukufaka abasubathi nge-coenzyme Q10 kungakhuphula ukutholwa komoya-mpilo ngo-12% futhi kufinyeze isikhathi sokululama sokuzivocavoca ngo-25%.
3, Amathemba esikhathi esizayo we-Coenzyme Q10
Ubuchwepheshe obusha bokubunjwa obufana nama-nanocarriers nama-liposomes buthuthukise kakhulu i-bioavailability ye-coenzyme Q10. Isibonelo, ama-nanoemulsions angakhuphula ukuvuthwa kwesikhumba se-coenzyme Q10 izikhathi ezintathu kanye ne-bioavailability yomlomo izikhathi ezingu-2.5.
Ucwaningo lwesicelo somtholampilo luyaqhubeka nokujula. Ucwaningo lwakamuva lubonisa ukuthi i-coenzyme Q10 inenani lokwelapha elingase libe khona ezifweni ze-neurodegenerative, izinkinga zesifo sikashukela, njll.
Amathemba emakethe abanzi. Kulindeleke ukuthi ngo-2025, usayizi wemakethe yomhlaba wonke we-coenzyme Q10 uzofinyelela ku-1.2 billion wamadola aseMelika, ngezinga lokukhula lonyaka elingaphezu kuka-10%. Ngokuqiniswa kokuguga kwabantu kanye nokwenza ngcono kokuqwashisa ngezempilo, isidingo se-coenzyme Q10 sizoqhubeka nokukhula.
Ukutholwa kanye nokusetshenziswa kwei-coenzyme Q10baye bavula inkathi entsha yemizamo yabantu yokulwa nokuguga. Ukusuka kumetabolism yamandla eselula kuya ekuvikelweni kwe-antioxidant, ukusuka ekunakekelweni kwesikhumba kuye ekuvimbeleni izifo, le molekyuli yomlingo ishintsha ukuqonda kwethu impilo nokuguga. Ngokuzayo, ngokuthuthuka kobuchwepheshe bokuqamba kanye nokujula kocwaningo lomtholampilo, i-coenzyme Q10 ngokungangabazeki izoletha ezinye izimanga empilweni yomuntu. Ekuphishekeleni ukuphila isikhathi eside nempilo, i-coenzyme Q10 izoqhubeka nokudlala indima yayo eyingqayizivele nebalulekile, ibhala isahluko esisha kusayensi yokuphila.
Isikhathi sokuthumela: Mar-11-2025
