I-Ergothionein (usawoti wangaphakathi we-mercapto histidine trimethyl)
I-Ergothionine(EGT) i-antioxidant yemvelo engavikela amaseli emzimbeni womuntu futhi iyinto ebalulekile esebenzayo emzimbeni.
Emkhakheni we-skincare, i-ergotamine inezindawo ezinamandla zokulwa ne-antioxidant. Inganciphisa ama-radicals mahhala, inciphise ukulimala kwe-oxidative, ivikele amangqamuzana esikhumba ezintweni zangaphandle zemvelo, isize ukubambezela ukuguga kwesikhumba, futhi igcine ukunwebeka nokukhazimula kwesikhumba.
Ngaphezu komkhakha we-skincare, i-ergotamine nayo inezinhlelo zokusebenza embonini yezemithi. Isibonelo, ekuthuthukisweni kweminye imithi, ingasetshenziswa njengesithako esisizayo ukusiza ukuthuthukisa ukuzinza nokusebenza komuthi. Emkhakheni wokudla, kukhona futhi izifundo ezihlola ukuthi kungenzeka yini ukuzisebenzisa njengesengezo sokudla ukuze kuthuthukiswe izakhiwo ze-antioxidant zokudla futhi andise impilo yakho yeshalofu.
I-Ergothionein inokuphepha okuphezulu. Emikhiqizweni ye-skincare, ukugcwala kwezithasiselo kuvame ukuhluka kuye ngefomula kanye nezidingo zokusebenza ngempumelelo zomkhiqizo, ngokuvamile zisuka ku-0.1% ziye ku-5%.
Indima ebalulekile
I-Antioxidant
I-Ergothionein ingasabela ngokushesha ngama-radicals mahhala ukuwaguqula abe yizinto ezingenabungozi, futhi ayilahleki kalula. Ngasikhathi sinye, ingagcina amazinga amanye ama-antioxidants (njengeVC kanye ne-glutathione), ngaleyo ndlela ivikela amangqamuzana esikhumba ekulimaleni kwe-oxidative.
Indlela yayo yokusebenza iwukuba ihlahle ngokuphumelelayo - i-OH (i-hydroxyl radicals), i-chelate divalent iron ion nama-ion ethusi, ivimbele i-H2O2 ukuthi ingakhiqizi - OH ngaphansi kwesenzo se-iron noma i-ion yethusi, ivimbele i-ion yethusi encike ku-oxidation ye-hemoglobin oxygenated, futhi ivimbele ukusabela kwe-peroxidation okukhuthaza i-arachidonic acid ngemva kwe-myoglobin (noma i-hemoglobin) ixutshwe ne-H2O2.
I-Antiinflammatory
Ukusabela kokuvuvukala ngaphakathi komzimba kuyimpendulo evamile yokuzivikela engokwemvelo ekushukumiseni, kanye nokubonakaliswa kokumelana komzimba nezinto ezilimazayo. I-Ergothionein ingavimbela ukukhiqizwa kwezinto ezivuvukalayo, inciphise izinga lokusabela kokuvuvukala, futhi inciphise ukungakhululeki kwesikhumba. Inikeza imiphumela yokulwa nokuvuvukala ngokulawula izindlela zokubonisa izimpawu ze-intracellular futhi ivimbele ukubonakaliswa kwezakhi zofuzo ezihlobene nokuvuvukala. Isibonelo, ngesikhumba esibucayi noma esinezinduna, i-ergotamine ingasiza ekunciphiseni ukuvuvukala futhi ikhuthaze ukulungiswa kwesikhumba.
Ukuvimbela ukuthwebula izithombe
I-Ergothionein ingavimbela ukuqhekeka kwe-DNA okubangelwa ukukhanya kwe-ultraviolet ne-hydrogen peroxide, futhi ingaphinde ikhiphe ama-radicals mahhala futhi imunce imisebe ye-ultraviolet ukuze iqede umonakalo ku-DNA. Ngaphakathi kwebanga lokumunca i-ultraviolet, i-ergothionein inobude beza beza obufana naleyo ye-DNA. Ngakho-ke, i-ergothionein ingasebenza njengesihlungi sokuphila semisebe ye-ultraviolet.
Njengamanje, ucwaningo oluningi luye lwabonisa ukuthi i-ergotamine iyisithako esisebenza kahle kakhulu sokuvikela ilanga esingavimbela ukulimala kwesikhumba emisebeni ye-UV.
Khuthaza ukukhiqizwa kwephrotheni ye-collagen
I-Ergothionein ingakhuthaza ukwanda kwenani lama-fibroblasts futhi ikhuthaze ukuhlanganiswa kwe-collagen ne-elastin. Ikhuthaza ukuvezwa kwezakhi zofuzo ze-collagen kanye nokuhlanganiswa kwamaprotheni ngokwenza kusebenze ama-molecule athile okubonisa ngaphakathi kwamaseli.
Isikhathi sokuthumela: Aug-08-2024