Ucwaningo nokuthuthukiswa kweI-pyridoxine tripalmitate
I-Pyridoxine Tripalmitate iphuma ku-B6 kuvithamini B6, ogcina ngokuphelele umsebenzi nokusebenza okuhambisanayo kwevithamini B6. Ama-acids amathathu e-palmitic axhunywe esakhiweni esiyisisekelo se-vitamin B6, eshintsha impahla yasekuqaleni encibilika emanzini ibe yi-lipophilic kanye ne-lipophilic properties, ngaleyo ndlela ithuthukise ukumuncwa nokuzinza. Ucwaningo selukhombisile ukuthi i-pyridoxine tripalmitate inezindawo ezinhle zokungena kwesikhumba, ingakhuphula ngempumelelo izinga lokumuncwa kwesikhumba kanye nokunqwabelana kwe-pyridoxine, futhi ithuthukise ukutholakala kwayo kwezicubu zesikhumba [1]. Ukuhlolwa kwe-in vitro kuphinde kwaqinisekisa ukuthi i-pyridoxine tripalmitate ingakhuthaza ukuhlanganiswa kwe-collagen futhi ivimbele i-matrix metalloproteinases, ifinyelele.ukuthambisa, anti-umbimbi kanye nemiphumela yokuguga.
Ukuhlolwa kokusebenza ngempumelelo kwe-pyridoxine tripalmitate
1. Ukunakekelwa kwesikhumba
Ingakwazi ukuvimbela umbala futhi igcine isikhumba simhlophe. Yakhoanti-inflammatorykanye nemisebenzi ye-collagen synthesis nayo ingathambisa isikhumba futhi igweme isikhumba esomile nesiqhekekile esibangelwa ukuntula. Ilawula ukusebenza kwezindlala ze-sebaceous futhi ingasetshenziswa njengomkhiqizo wokulawula uwoyela wesikhumba.
2. Ukunakekelwa kwezinwele
Omunye wemisebenzi evelele kakhulu ukuvikela izinwele kanyeivimbele ukuthi ingawi. Idlala indima ebalulekile enqubweni yokukhula kwezinwele ezintsha kusuka ezinweleni zezinwele. Uma umzimba untula i-B6, uphawu oluvamile yi-seborrheic dermatitis esikhumbeni, engabangela kakhulu ukuqothuka kwezinwele.
Isizathu siwukuthiukukhula kwezinweleidinga amangqamuzana omama we-follicle yezinwele ukuze ahlanganise ama-amino acid esibabule, futhi le nqubo idinga ukubamba iqhaza kanye ne-catalysis ye-vitamin B6. Uma inganele, amangqamuzana ezinwele ze-follicle awakwazi ukukhula izinwele kahle, umjikelezo wokukhula kwezinwele uphoqeleka ukuba ube mfushane, futhi kulula ukuwa [2].
I-seborrheic dermatitis nayo ingabhebhethekisa ukuvuvukala kwezinhlayiya zezinwele, kubangele izinwele zibe brittle futhi ziqhekeke. Ngakho-ke, i-vitamin B6 eyanele ephuma ku-pyridoxine tripalmitate ibaluleke kakhulu ukuze kuqinisekiswe ukukhula kwezinwele ezijwayelekile kanye nempilo yezinwele. Ivimbela ukulahleka kwezinwele futhi iphinde ithuthukise izinkinga ze-seborrheic scalp.
Izicelo ze-pyridoxine tripalmitate
I-Pyridoxine tripalmitate iphuma ku-liposomal kavithamini B6. Ixhuma amaqembu amathathu e-palmitic acid ku-molecule ye-pyridoxine, ngakho-ke uvithamini B6, ekuqaleni oncibilika kakhulu emanzini, uba lipophilic kanye ne-lipophilic.
Lo mklamo wesakhiwo uthuthukisa kakhulu ukuncibilika kukawoyela kanye ne-lipophilicity ye-pyridoxine tripalmitate. Iyancibilika kuwoyela namanzi futhi incibilika kakhulu emafutheni nakumatikuletsheni onamafutha. Lokhu akugcini nje ukuthuthukisa ukuhlobana kwayo ne-lipid cell membrane, kodwa futhi kwenza kube lula ukungena kwezicubu zesikhumba futhi kudonswe isikhumba.
Ngasikhathi sinye, ukwengezwa kwamaqembu e-lipophilic kuthuthukisa nokuzinza kwe-pyridoxine tripalmitate, kugwema ukushiyeka kokuncibilika kwamanzi okujwayelekile.vitamin B6i-hydrolyzed kalula futhi ilahlekelwe umsebenzi. Ngakho-ke, i-bioavailability kanye nomphumela wokunakekelwa kwesikhumba we-pyridoxine tripalmitate ingcono kunaleyo kavithamini B6 uqobo.
Isikhathi sokuthumela: Mar-08-2024