I-Pyrroloquinoline Quinone, i-antioxidant enamandla kanye nokuvikelwa kwe-Mitochondrial kanye nokuthuthukisa amandla

I-Pyrroloquinoline Quinone(PQQ)

I-Pyrroloquinoline Quinone, i-antioxidant enamandla nokuvikelwa kwe-Mitochondrial kanye nokuthuthukisa amandla Isithombe Esifakiwe

Incazelo emfushane:

I-PQQ (i-Pyrroloquinoline Quinone) iyi-cofactor enamandla ye-redox ethuthukisa ukusebenza kwe-mitochondrial, ithuthukisa impilo yengqondo, futhi ivikele amangqamuzana ekucindezelekeni kwe-oxidative - esekela ubungqabavu ezingeni eliyisisekelo.

Igama Lohwebo:I-Cosmate®PQQ

Igama Lomkhiqizo:I-Quinone ye-Pyrroloquinoline

INCI Igama:I-Quinone ye-Pyrroloquinoline

I-Molecular Formula:I-C14H6N2O8

Inombolo ye-CAS:72909-34-3

Imilayezo eku-inthanethi I-imeyili WhatsApp

Imininingwane Yomkhiqizo

Kungani iZhonghe Fountain

Omaka bomkhiqizo

I-Quinone ye-Pyrroloquinoline (I-PQQ) iyinhlanganisela eyenzeka ngokwemvelo, efana ne-vitamin etholakala emhlabathini, ezitshalweni, nasekudleni okuthile (njenge-kiwifruit, isipinashi, nobhontshisi wesoya ovutshiwe). Isebenza njenge-coenzyme enamandla ye-redox, edlala indima ebalulekile ekukhiqizweni kwamandla amaselula, ukuzivikela kwe-antioxidant, kanye nezindlela zokubonisa amaseli. Ngokungafani nama-antioxidants amaningi, i-PQQ ikhuthaza ngenkuthalo ukukhiqizwa kwe-mitochondria entsha (mitochondrial biogenesis), ikakhulukazi ezithweni ezidinga amandla njengobuchopho nenhliziyo. Ikhono layo eliyingqayizivele lokudlula izinkulungwane zemijikelezo ye-redox iyenza iphumelele ngendlela ehlukile ekulweni nengcindezi ye-oxidative futhi isekele izinqubo eziyisisekelo zebhayoloji ukuze uthole impilo ephezulu nokuphila isikhathi eside.

Umsebenzi obalulekile we-PQQ:
Ishukumisa i-biogenesis ye-mitochondrial futhi ithuthukise ukukhiqizwa kwamandla (ATP) ngaphakathi kwamaseli.
Ukusekelwa kwe-Mitochondrial & umfutho wamandla: Ivuselela i-mitochondrial biogenesis (ikhulisa inombolo yabo), ithuthukisa ukusebenza kwe-mitochondrial, futhi ithuthukise ukukhiqizwa kwamandla kwamaselula, kusize ekudambiseni ukukhathala.
Umsebenzi onamandla wokulwa ne-antioxidant: Ithambisa ama-radicals mahhala ngempumelelo, inciphisa ukucindezelwa kwe-oxidative, futhi ivikele amaseli emonakalweni obangelwa izinhlobo ze-oxygen esebenzayo.
Imiphumela ye-Neuroprotective: Ithuthukisa ukuhlanganiswa kwezici zokukhula kwezinzwa, isekela ukukhula nokuphila kwama-neurons, futhi ingase ithuthukise imisebenzi yokuqonda njengenkumbulo nokugxila.
Izakhiwo zokulwa nokuvuvukala: Ivimbela ukukhululwa kwezinto ezibangela ukuvuvukala, kusiza ukunciphisa ukuvuvukala okungapheli okuhlobene nezifo ezihlukahlukene.
Ukulawulwa kwe-Metabolic: Ingase ithuthukise ukuzwela kwe-insulin, isize kushukela wegazi kanye nebhalansi ye-lipid, futhi isekele impilo yonke ye-metabolic.
Indlela Yesenzo:
I-Redox Cycling: I-PQQ isebenza njengesithwali se-electron esisebenza kahle kakhulu, esibhekana nokuncishiswa okuqhubekayo kanye ne-oxidation (imijikelezo engu-20,000+), idlula kude ama-antioxidants avamile afana ne-Vitamin C. Lokhu kunciphisa ama-radicals mahhala futhi kunciphisa ukucindezelwa kwe-oxidative.
I-Mitochondrial Biogenesis: I-PQQ ivula izindlela zokusayina ezibalulekile (ikakhulukazi i-PGC-1α kanye ne-CREB) eqala ukudalwa kwe-mitochondria entsha, enempilo futhi ithuthukise umsebenzi walezo ezikhona.
I-Nrf2 Activation: Iphakamisa indlela ye-Nrf2, ikhulise ukukhiqizwa komzimba okungapheli kwama-enzyme anamandla e-antioxidant (glutathione, SOD).
I-Neuroprotection: Isekela i-Nerve Growth Factor (NGF) synthesis futhi ivikela ama-neurons emonakalweni we-oxidative kanye ne-excitotoxicity.
Ukusayinwa Kweseli: Kushintshanisa umsebenzi wama-enzyme abandakanyeka emisebenzini ebalulekile yamaselula njengokukhula, ukuhlukanisa, nokuphila.Izinzuzo Nezinzuzo:
Amandla Eselula Asekelwe: Ithuthukisa ngokuphawulekayo ukusebenza kahle nokuminyana kwe-mitochondrial, okuholela ekwandeni kokukhiqizwa kwe-ATP nokunciphisa ukukhathala.
Umsebenzi Wokuqonda Obukhali: Usekela inkumbulo, ukugxila, ukufunda, kanye nempilo yobuchopho iyonke ngokuvikela izinzwa nokuthuthukisa i-neurogenesis.
I-Potent Antioxidant Defense: Inikeza isivikelo esikhethekile, esihlala isikhathi eside ekulimaleni kwe-oxidative kuwo wonke umzimba.
Ukwesekwa kwe-Cardiometabolic: Kuthuthukisa ukusebenza kwenhliziyo okunempilo futhi kungase kusekele umzimba weshukela wegazi onempilo.
Ukuvuselelwa Kweselula: Kukhuthaza ukukhula nokuvikelwa kwamaseli anempilo ngenkathi kunciphisa umonakalo.
Amandla we-Synergistic: Isebenza ngamandla eduze nezinye izakhamzimba ze-mitochondrial njenge-CoQ10/Ubiquinol.
Iphrofayela Yokuphepha: Iqashelwa njengephephile (isimo se-GRAS e-US) enemiphumela engemihle emincane ngemithamo enconyiwe.
Imininingwane Ebalulekile Yezobuchwepheshe

Izinto	Imininingwane
Ukubukeka	Impushana Ensundu Ebomvu
I-Identification(A233/A259)UV Absorbance(A322/A259)	0.90±0.09
I-Identification(A233/A259)UV Absorbance(A322/A259)	0.56±0.03
Ukulahlekelwa Ekumisweni	≤9.0%
Izinsimbi Ezisindayo	≤10ppm
I-ARSENIC	≤2ppm
I-Mercury	≤0.1ppm
Ukuhola	≤1ppm
Isilinganiso se-Sodium/PQQ	1.7-2.1
I-HPLC Purity	≥99.0%
Isibalo se-Aerobic esiphelele	≤1000cfu/g
Ukubalwa kwemvubelo nesikhunta	≤100cfu/g

Izinhlelo zokusebenza.

I-Antioxidant Enamandla: I-PQQ ivikela ngokuqinile isikhumba emonakalweni obangelwa imisebe ye-UV, ukungcola, kanye nengcindezi ngokuqeda ama-radicals ayingozi, isiza ukuvikela ukuguga ngaphambi kwesikhathi.
Iqinisa Amandla Esikhumba Futhi Ilwe Nokuguga: Isiza amangqamuzana esikhumba ukuthi akhiqize amandla engeziwe (ngokusekela i-mitochondria), engathuthukisa ukuqina, inciphise imibimbi, futhi ikhuthaze ukubukeka kobusha.
Ikhanyisa Ithoni Yesikhumba: I-PQQ isiza ekwehliseni amabala amnyama kanye ne-hyperpigmentation ngokuvimbela ukukhiqizwa kwe-melanin, okuholela ekukhanyeni kwebala nakakhulu.