I-Cosmate®SM, i-Silymarin ibhekisela eqenjini lama-antioxidant e-flavonoid atholakala ngokwemvelo ezinhlamvini zethistle yobisi (ezazisetshenziswa ngokomlando njengekhambi lobuthi bamakhowe). Izingxenye ze-Silymarin yi-Silybin, i-Silibinin, i-Silydianin, ne-Silychristin. Lezi zinhlanganisela zivikela futhi zelaphe isikhumba ekucindezelekeni kwe-oxidative okubangelwa emisebeni ye-ultraviolet. I-Cosmate®SM, i-Silymarin nayo inezici ezinamandla zokulwa ne-antioxidant ezandisa impilo yamaseli. I-Cosmate®SM, i-Silymarin ingavimbela ukulimala kokuchayeka kwe-UVA ne-UVB. Iphinde icwaningwe ngekhono layo lokuvimbela i-tyrosinase (i-enzyme ebalulekile ye-melanin synthesis) kanye ne-hyperpigmentation. Ekulapheni kwesilonda kanye nokulwa nokuguga, i-Cosmate®SM, i-Silymarin ingavimbela ukukhiqizwa kwama-cytokines ashayela ukuvuvukala kanye nama-enzyme e-oxidative. Ingase futhi ikhulise ukukhiqizwa kwe-collagen kanye ne-glycosaminoglycans (GAGs), ikhuthaze inhlanzi ebanzi yezinzuzo zezimonyo. Lokhu kwenza i-compound ibe yinhle kuma-antioxidant serums noma njengesithako esibalulekile kuma-sunscreens.