I-Cosmate®I-ZnPCA,Zinc PCA iwusawoti we-zinc oncibilika emanzini osuselwa ku-PCA, i-amino acid eyenzeka ngokwemvelo ekhona esikhumbeni.Iyinhlanganisela ye-zinc ne-L-PCA, isiza ukulawula ukusebenza kwezindlala ze-sebaceous futhi inciphisa izinga le-sebum yesikhumba ku-vivo. Isenzo saso ekwandeni kwamagciwane, ikakhulukazi ku-Propionibacterium acnes, kusiza ukunciphisa ukucasuka okuwumphumela.