Ukwenza mhlophe kwesikhumba i-ethylbisiminomethylguaiacol manganese chloride

Incazelo emfushane:

I-Ethyleneiminomethylguaiacol manganese chloride, eyaziwa nangokuthi i-EUK-134, iyingxenye yokwenziwa ehlanzeke kakhulu elingisa umsebenzi we-superoxide dismutase (SOD) kanye ne-catalase (CAT) ku-vivo.I-EUK-134 ibonakala iyimpushana yekristalu ensundu ngokubomvu enephunga elincane eliyingqayizivele.Incibilika kancane emanzini futhi inyibilika kuma-polyols njenge-propylene glycol.Iyabola lapho ichayeke ku-asidi. I-Cosmate®EUK-134, iyinhlanganisela ye-molecule encane yokwenziwa efana nomsebenzi we-antioxidant enzyme, kanye nengxenye enhle kakhulu ye-antioxidant, engakhanyisa ithoni yesikhumba, ilwe nokulimala kokukhanya, ivimbele ukuguga kwesikhumba, futhi inciphise ukuvuvukala kwesikhumba. .

Igama Lohwebo:I-Cosmate®EUK-134

Igama lomkhiqizo:I-Ethyleneiminomethylguaiacol manganese chloride

INCI Igama:I-Ethyleneiminomethylguaiacol manganese chloride

I-Molecular Formula:I-C18H18CLMNN204

Inombolo ye-CAS:81065-76-1

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Imininingwane Yomkhiqizo

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Omaka bomkhiqizo

I-Cosmate®I-EUK-134umkhiqizo omusha owenziwe ngokusekelwe ku-SOD.Njengenhlanganisela ye-molecule encane, i-EUK-134 ingangena ngokuqondile esikhumbeni futhi isebenzise imiphumela yayo, ixazulule inkinga yama-molecule amakhulu e-SOD nokuzinza okubi.Njengenye yezinto zokusetshenziswa kwezimonyo, i-EUK-134 inomsebenzi ombaxambili futhi ingaqeda ama-superoxide radicals.Inemiphumela yokukhanyisa isikhumba, ukuthuthukisa isikhumba esinamafutha, ukunciphisa ukuvuvukala kwesikhumba, nokugcina ukubonakala kwesikhumba nokuba mhlophe.Iphinde ibe nekhono lokuvuselela nokuzinza okungcono kune-SOD ne-CAT.Ngokusekelwe ezicini zayo eziqinile ze-antioxidant nezivuselelayo, i-EUK-134 izosetshenziswa kakhulu emikhakheni efana nezimonyo ezilwa nokuguga, izimonyo zokuvikela ilanga, izimonyo ezimhlophe, nemikhiqizo yokulungisa isikhumba.

Amapharamitha wobuchwepheshe:

Ukubukeka	I-Amorphous Powder
Umbala	Okunsundu ngokubomvu
Iphunga	Okucacile Kancane
Ubumsulwa	＞99%

Indlela ye-Antioxidant

Indlela ye-Antioxidant:ngomjikelezo we-redox we-Mn(II), i-superoxide anion(o2) iguqulwa ibe yi-peroxide(H2O2), bese i-hydrogen peroxide iguqulwa ibe amanzi(H2O)

Ngempumelelo futhi ulungise i-UV edalwe ukuguqulwa kwe-DNA

I-Thymine dimer(TT dimer) yipheya lezisekelo ze-thymine eziboshwe ngamakhemikhali ngendlela engavamile ku-DNA, okubangelwa umonakalo obangelwa imisebe ye-ultraviolet.Ukuchayeka kwesikhumba ekukhanyeni kwe-ultraviolet kungaholela ekuxhumekeni kwe-thymine ku-DNA.

Yehlisa ngempumelelo i-erythema ne-lipid peroxidation ebangelwa ukukhanya kwe-ultraviolet; lungisa umonakalo